224 x 30 minute episodes
A West Virginia mountain family picks up `stakes' and moves to a ranch in California's San Fernando Valley. Center of the action, and undisputed star of the show, was Grandpa, a porch-rockin', gol-darnin', consarnin' old geezer with a wheezy voice who liked to meddle in practically everybody's affairs, neighbors and kin alike.
His kin were grandson Luke and his new bride, Kate; Luke's teenage sister, Hassie; and Luke's 11-year-old brother, Little Luke (their parents were deceased). Completing the regular cast were Pepino, their loyal farmhand; George MacMichael, their crusty neighbor and Amos' best friend; and Flora, George's spinster sister who had eyes for Amos.
1957 / 1963 - Danny Thomas, Brennan-Westgate Productions & VT&L Productions
David Alexander, Hy Averback, Richard Crenna, Sidney Miller
Walter Brennan (Grandpa Amos McCoy), Richard Crenna (Luke McCoy), Kathy Nolan (Kate McCoy/1957-1952), Lydia Reed (Aunt Hassie), Michael Winkleman (Little Luke/1957-1962), Tony Martinez (Pepino Garcia), Andy Clyde (George MacMichael), Madge Blake (Flora MacMichael), Betty Garde (Aggie Larkin/1959-1960), Janet De Gore (Louise Howard/1963), Butch Patrick (Greg Howard/1963), Joan Blondell (Winifred Jordan/1963)